The Israel Innovation Authority and the U.S Department of Energy invite Israeli researchers from industry and academia to learn about The Trillion Parameters Consortium (TPC) model and explore its research collaboration opportunities. Achieving the promise of large-scale, AI 'foundation' models for scientific discovery, supporting activities ranging from self-driving laboratories to hypothesis generation, will require unprecedented scale of computation to train large-scale AI models, coupled with an enormous, inherently multidisciplinary task of preparing diverse scientific data for use in model training, evaluating the trustworthiness and safety of models, and supporting their use. Only a relatively small number of organizations have the resources to build models at state-of-the-art scales (e.g., trillions of parameters, trained using many trillions of tokens), yet many such projects are being undertaken around the world. These involve multiple facets of work including preparing and tokenizing scientific data; model design, testing, scaling, and pre-training; and evaluation with respect to trustworthiness, safety, and ethics. Formed in 2023 by leaders of these projects from around the world, TPC convenes online discussions and in-person workshops to enable participants to collaborate in order to reduce duplication of human and computational effort (share data, methods, even models/weights), to accelerate progress (joint evaluation of tools, optimization on specific platforms, etc.), and to improve outcomes (sharing evaluation tools, jointly improve methods/frameworks/workflows, etc.). TPC emphasizes the value of open systems, while recognizing the constraints associated with organizational, national, and regional guidelines. Please note – the Israel Innovation Authority is not a partner of TPC and is only bringing up this collaboration opportunity as part of its strategy to introduce development opportunities to the Israeli ecosystem.